7 days old

Sr Associate Scientist - Computational Biologist

Amgen
South San Francisco, CA 94080
  • Job Code
    119209658
Amgen

Job ID: R-96785
Location: South San Francisco, CA, US 94083

The Department of Genome Analysis Unit at Amgen South San Francisco (ASF) is looking for a computational biology/Bioinformatics Senior Associate Scientist with expertise in analyzing high-content NGS relevant data as well as other non-NGS OMICS data, such as proteomics and flow cytometry. The primary responsibilities would be to conduct computational and statistical analyses on RNA-seq, proteomics, metabolomics, flow cytometry and other high-content data for target validation and toxicity of drug candidates. The tasks require applying sophisticated statistical methods and/or deep-learning machine learning models. Experience with analytical method development is preferable.

The Computational biology/Bioinformatics Senior Associate Scientist will work with biologists in immuno-oncology, cardiovascular relevant disease fields as well as toxicology to leverage information on our targeted biological pathways along with computational algorithms to manage and mine internal and external NGS sequencing and other high-content databases. The successful candidate is expected to interface with the local statistical genetics/computational biology/bioinformatics community, particularly in evaluating new opportunities that advance the target discovery, target validation and toxicity evaluation.

Basic Qualifications

Master's and 3 years statistical genetics experience

OR

Bachelor's and 3 years statistical genetics experience

Preferred Qualifications

Doctorate degree or Doctorate degree completed by June 2020

PhD in Computational Biology, Bioinformatics, Mathematics, Statistics, Statistical Genetics or related fields

Three or more years of research experience in relevant fields

A working knowledge of applied mathematics or statistics to analyze large-scale omics data sets/biobanks

Ability to translate biological and medical questions into analytical models providing actionable results

Programming experience in languages such as R, Python or Matlab

Enjoys working in collaborative team environment

Track record of high impact publications in relevant fields and name journals

A strong scientific background with training in genomics, bioinformatics and computational biology

Strong written and oral communication skills, self-motivation, independence and leadership

Experience understanding the sources of bias arising from NGS high-content platforms, especially RNA-seq and single-cell RNA-seq

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

PI119209658

<b>Amgen</b><br/><br/><b>Job ID: </b>R-96785<br/><b>Location: </b>South San Francisco, CA, US 94083<br/><br/>The Department of Genome Analysis Unit at Amgen South San Francisco (ASF) is looking for a computational biology/Bioinformatics Senior Associate Scientist with expertise in analyzing high-content NGS relevant data as well as other non-NGS OMICS data, such as proteomics and flow cytometry. The primary responsibilities would be to conduct computational and statistical analyses on RNA-seq, proteomics, metabolomics, flow cytometry and other high-content data for target validation and toxicity of drug candidates. The tasks require applying sophisticated statistical methods and/or deep-learning machine learning models. Experience with analytical method development is preferable.<br><br>The Computational biology/Bioinformatics Senior Associate Scientist will work with biologists in immuno-oncology, cardiovascular relevant disease fields as well as toxicology to leverage information on our targeted biological pathways along with computational algorithms to manage and mine internal and external NGS sequencing and other high-content databases. The successful candidate is expected to interface with the local statistical genetics/computational biology/bioinformatics community, particularly in evaluating new opportunities that advance the target discovery, target validation and toxicity evaluation.<br><br><b> Basic Qualifications </b><br><br>Master's and 3 years statistical genetics experience<br><br>OR<br><br>Bachelor's and 3 years statistical genetics experience<br><br><b>Preferred Qualifications</b><br><br>Doctorate degree or Doctorate degree completed by June 2020<br><br>PhD in Computational Biology, Bioinformatics, Mathematics, Statistics, Statistical Genetics or related fields<br><br> Three or more years of research experience in relevant fields <br><br>A working knowledge of applied mathematics or statistics to analyze large-scale omics data sets/biobanks<br><br>Ability to translate biological and medical questions into analytical models providing actionable results<br><br>Programming experience in languages such as R, Python or Matlab<br><br>Enjoys working in collaborative team environment<br><br> Track record of high impact publications in relevant fields and name journals <br><br>A strong scientific background with training in genomics, bioinformatics and computational biology <br><br>Strong written and oral communication skills, self-motivation, independence and leadership <br><br>Experience understanding the sources of bias arising from NGS high-content platforms, especially RNA-seq and single-cell RNA-seq<br><br>Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.<br><br>We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.<br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. <br> <br> Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.<br/><br/> <img src="https://analytics.click2apply.net/v/7ed1Ezcn8RJgfZ1NF7Y5y"> <p>PI119209658</p>

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Posted: 2020-03-21 Expires: 2020-04-21

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Sr Associate Scientist - Computational Biologist

Amgen
South San Francisco, CA 94080

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