13 days old

Senior Associate Scientist - Structural Biology

Amgen
Thousand Oaks, CA 91360
  • Job Code
    114955591
Amgen

Job ID: R-86960
Location: Thousand Oaks, CA, US 91360

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen (Thousand Oaks, CA.) seeks a Senior Associate Scientist in protein biochemistry and crystallography to join its structural biology group.

The Amgen research laboratory provides comprehensive molecular insight and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various important therapeutic areas. The Senior Associate Scientist will be part of a growing structural biology group and will be responsible for designing and purifying target proteins for Cryo-Electron Microscopy and X-ray crystallography, assisting in data collection and resolution of complex molecular structures.

Basic Qualifications

Master's degree and 3 years of Structural Biology experience

OR

Bachelor's degree and 5 years of Structural Biology experience

Preferred Qualifications
  • Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, crystallization, structure determination and analysis
  • Experience with single particle cryo-EM process (including sample/grid preparation and screening, data collection and processing, three-dimensional reconstruction and model building)
  • Excellent presentation skills (written and oral) that enhance team-based progress
  • Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment


Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

PI114955591

<b>Amgen</b><br/><br/><b>Job ID: </b>R-86960<br/><b>Location: </b>Thousand Oaks, CA, US 91360<br/><br/>Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen (Thousand Oaks, CA.) seeks a Senior Associate Scientist in protein biochemistry and crystallography to join its structural biology group.<br><br>The Amgen research laboratory provides comprehensive molecular insight and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various important therapeutic areas. The Senior Associate Scientist will be part of a growing structural biology group and will be responsible for designing and purifying target proteins for Cryo-Electron Microscopy and X-ray crystallography, assisting in data collection and resolution of complex molecular structures.<br><br><b>Basic Qualifications </b><br><br>Master's degree and 3 years of Structural Biology experience<br><br>OR<br><br>Bachelor's degree and 5 years of Structural Biology experience<br><br><b>Preferred Qualifications </b><br><ul><li>Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, crystallization, structure determination and analysis</li><li>Experience with single particle cryo-EM process (including sample/grid preparation and screening, data collection and processing, three-dimensional reconstruction and model building)</li><li>Excellent presentation skills (written and oral) that enhance team-based progress</li><li>Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment</li></ul><br><br>Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.<br><br>Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.<br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.<br/><br/> <img src="https://analytics.click2apply.net/v/g2o6aGh7nyzQTxaAIlr4k"> <p>PI114955591</p>

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Posted: 2019-10-30 Expires: 2019-11-30

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Senior Associate Scientist - Structural Biology

Amgen
Thousand Oaks, CA 91360

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