13 days old

Scientist - Medicinal Chemistry

Amgen
Thousand Oaks, CA 91360
  • Job Code
    114955993
Amgen

Job ID: R-86871
Location: Thousand Oaks, CA, US 91360

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks, CA (ATO).

This Scientist role will be part of an innovative Medicinal Chemistry group, with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Scientist will devise and implement state of the art scientific research through conducting laboratory experiments, planning detailed procedures for defined projects including timelines, milestones, methodological approaches, expected results and necessary resources; reviewing, analyzing, and interpreting scientific data and results; providing regular updates, documentation, and/or communication on project results; collaborating with other scientists and keeping current with field of expertise, including literature and technology development. Additional responsibilities may include advising supervisors and colleagues in areas of expertise; participating in national and international meetings, providing scientific results that support the generation of publications or patents, and mentoring research associates and laboratory assistants.

Basic Qualifications
  • Doctorate degree OR Doctorate degree completed by August 2020
  • OR
  • Master's degree and 4 years of laboratory experience
  • OR
  • Bachelor's degree and 6 years of laboratory experience


Preferred Qualifications
  • Chemistry degree specializing in organic synthesis
  • Consistent track record of academic accomplishments (e.g., peer-reviewed publications and/or patents)
  • Demonstration of good lab practices, with particular attention to safety
  • Clear understanding of structural determination using NMR and MS techniques as well as knowledge of related purification methods
  • Understanding of biological and pharmaceutical principles and a working knowledge of the use of structure-based or other computer-aided drug design tools
  • Knowledge of the application of parallel synthesis techniques to medicinal chemistry
  • Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams


Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live cell-therapies.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

PI114955993

<b>Amgen</b><br/><br/><b>Job ID: </b>R-86871<br/><b>Location: </b>Thousand Oaks, CA, US 91360<br/><br/>Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks, CA (ATO).<br><br>This Scientist role will be part of an innovative Medicinal Chemistry group, with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Scientist will devise and implement state of the art scientific research through conducting laboratory experiments, planning detailed procedures for defined projects including timelines, milestones, methodological approaches, expected results and necessary resources; reviewing, analyzing, and interpreting scientific data and results; providing regular updates, documentation, and/or communication on project results; collaborating with other scientists and keeping current with field of expertise, including literature and technology development. Additional responsibilities may include advising supervisors and colleagues in areas of expertise; participating in national and international meetings, providing scientific results that support the generation of publications or patents, and mentoring research associates and laboratory assistants.<br><br><b>Basic Qualifications </b><br><ul><li>Doctorate degree OR Doctorate degree completed by August 2020</li><li>OR</li><li>Master's degree and 4 years of laboratory experience</li><li>OR</li><li>Bachelor's degree and 6 years of laboratory experience</li></ul><br><br><b>Preferred Qualifications </b><br><ul><li>Chemistry degree specializing in organic synthesis</li><li>Consistent track record of academic accomplishments (e.g., peer-reviewed publications and/or patents)</li><li>Demonstration of good lab practices, with particular attention to safety</li><li>Clear understanding of structural determination using NMR and MS techniques as well as knowledge of related purification methods</li><li>Understanding of biological and pharmaceutical principles and a working knowledge of the use of structure-based or other computer-aided drug design tools</li><li>Knowledge of the application of parallel synthesis techniques to medicinal chemistry</li><li>Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams</li></ul><br><br>Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.<br><br>Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live cell-therapies.<br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.<br/><br/> <img src="https://analytics.click2apply.net/v/6e57JAUzneGLf8lwCoqNG"> <p>PI114955993</p>

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Posted: 2019-10-30 Expires: 2019-11-30

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Scientist - Medicinal Chemistry

Amgen
Thousand Oaks, CA 91360

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