29 days old

Process Development Senior Scientist - Drug Product Technology Department

Amgen
Thousand Oaks, CA 91360
  • Job Code
    118538281
Amgen

Job ID: R-94862
Location: Thousand Oaks, CA, US 91360

Job Description:

The Synthetics Enabling Technology (SET) group within the Drug Product Technologies (DPT) department of Amgen in Thousand Oaks, CA is seeking an enthusiastic, highly motivated, and team-oriented scientist for the position of Process Development Sr. Scientist. SET is a key DPT interface with partners in Process Development, Discovery Research, and Translational Sciences. Within this space Synthetics Enabling Technologies:

· Provides synthetics molecule assessment (developability assessment) and preclinical formulation support

· Enables lead optimization and form selection to meet discovery research and process development requirements (Target Product Profile).

· Utilizes predictive in silico and in vitro models to support molecule and biopharmaceutical assessments and identify development strategies

· Provides early clinical support for synthetics liquid dosage forms (e.g. drug-in-bottle, parenteral, inhalation, topical) and conducts technical transfers to support clinical manufacturing (GMP).

In this role, the Sr. scientist will support these activities and represent SET on both Discovery Research and Early Development teams, providing functional area expertise.

Basic Qualifications:

Doctorate degree and 2 years of scientific experience

OR

Master's degree and 5 years of scientific experience

OR

Bachelor's degree and 7 years of scientific experience

Preferred Qualifications:

Doctorate Degree with 5+ years of industrial experience in Pharmaceutics, Pharmacy, Chemistry or related field

Experience in non-oral drug delivery systems (e.g. parenteral, inhalation and/or topical) and be able to lead the formulation development and guide the drug product manufacturing

Experience in preformulation techniques including HPLC analysis, physicochemical evaluation (solubility, stability, pKa and LogP determination, etc.) and solid-state characterization (DSC, TGA, XRPD, microscopy, moisture sorption, particle characterization, etc.)

Experience in Pharmacokinetic or Biopharmaceutical modeling software

Experience in physical form screening and selection

Abilities to take initiative, conduct independent pharmaceutics research and be flexible in responsibilities

Excellent oral and written communication skills for timely documentation, presentation, and discussion of scientific results in a fast-paced, multi-disciplinary, team-based environment

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

PI118538281

<b>Amgen</b><br/><br/><b>Job ID: </b>R-94862<br/><b>Location: </b>Thousand Oaks, CA, US 91360<br/><br/><b> Job Description: </b><br><br>The Synthetics Enabling Technology (SET) group within the Drug Product Technologies (DPT) department of Amgen in Thousand Oaks, CA is seeking an enthusiastic, highly motivated, and team-oriented scientist for the position of Process Development Sr. Scientist. SET is a key DPT interface with partners in Process Development, Discovery Research, and Translational Sciences. Within this space Synthetics Enabling Technologies:<br><br> Provides synthetics molecule assessment (developability assessment) and preclinical formulation support<br><br> Enables lead optimization and form selection to meet discovery research and process development requirements (Target Product Profile).<br><br> Utilizes predictive in silico and in vitro models to support molecule and biopharmaceutical assessments and identify development strategies<br><br> Provides early clinical support for synthetics liquid dosage forms (e.g. drug-in-bottle, parenteral, inhalation, topical) and conducts technical transfers to support clinical manufacturing (GMP).<br><br>In this role, the Sr. scientist will support these activities and represent SET on both Discovery Research and Early Development teams, providing functional area expertise.<br><br><b>Basic Qualifications:</b><br><br> Doctorate degree and 2 years of scientific experience <br><br> OR <br><br> Master's degree and 5 years of scientific experience <br><br> OR <br><br> Bachelor's degree and 7 years of scientific experience <br><br><b>Preferred Qualifications:</b><br><br>Doctorate Degree with 5+ years of industrial experience in Pharmaceutics, Pharmacy, Chemistry or related field<br><br>Experience in non-oral drug delivery systems (e.g. parenteral, inhalation and/or topical) and be able to lead the formulation development and guide the drug product manufacturing<br><br>Experience in preformulation techniques including HPLC analysis, physicochemical evaluation (solubility, stability, pKa and LogP determination, etc.) and solid-state characterization (DSC, TGA, XRPD, microscopy, moisture sorption, particle characterization, etc.)<br><br>Experience in Pharmacokinetic or Biopharmaceutical modeling software<br><br>Experience in physical form screening and selection<br><br>Abilities to take initiative, conduct independent pharmaceutics research and be flexible in responsibilities<br><br>Excellent oral and written communication skills for timely documentation, presentation, and discussion of scientific results in a fast-paced, multi-disciplinary, team-based environment<br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.<br/><br/> <img src="https://analytics.click2apply.net/v/j7V5ZGIjEKbRsRZ6uxLV2"> <p>PI118538281</p>
Posted: 2020-02-29 Expires: 2020-03-31

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Process Development Senior Scientist - Drug Product Technology Department

Amgen
Thousand Oaks, CA 91360

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