1+ months

Bioanalytical Development Specialist - Precision Biomarker Labs

Cedars-Sinai Medical Center
Los Angeles, CA 90006
**Join us a method development scientist in bioanalytical mass spectrometry at Cedars-Sinai Medical Center!** The newly formed Precision Biomarker Laboratory, housed within the Advanced Biosystems Research Institute, is dedicated to developing advanced technologies for the treatment and diagnosis of disease. To learn more, visit https://www.cedars-sinai.org/research/departments-institutes/advanced-clinical-biosystems.html . We are seeking a candidate with hands-on experience in the development and validation of laboratory tests for proteins, peptides, and endogenous small molecules. Working in a brand-new laboratory fully equipped with state-of-the-art LC-MS/MS equipment and ultra-sensitive immunoassay platforms, you will develop, validate and transfer high quality quantitative assays and relevant diagnostic tests to a production environment. You will also participate in grant funded development and translation of novel diagnostic tests. **Primary Duties and Responsibilities:** + Performs tasks related to the project under supervision of a senior scientist. + Develops LC-MS/MS assays for the quantitative analysis of proteins, peptide, and endogenous small molecules + Maintains good documentation practices and ensures all documentation compliances with all Federal and State accrediting agency requirements, including the Food and Drug Administration (FDA) and College of American Pathologists (CAP/CLIA) requirements as necessary. + Writes or aids in the writing of standard operating procedures (SOPs) and validation reports. + Uses and maintains high complexity lab equipment. + Verifies samples received, logs samples into systems, and transports to appropriate environment within the facility for storage following SOPs. + Maintains material inventories and ensures all equipment and materials are ready for project tasks. + Participates in research activities or protocols involving all aspects of the process, including investigation, technical, testing/validation of results, and report findings. + Performs lab maintenance duties as required, including glassware cleaning. **Department-Specific Responsibilities:** + Development of robust methods for the quantitation of small molecules and peptides using LC-MS/MS. + Operation of Thermo and Sciex mass spectrometry platforms for both low and high resolution analysis techniques. + Operation of HPLC equipment for the separation of analytes in complex matricies. + Use of mass spectrometry analysis software (vendor specific and open source) for qualitative and quantitative characterization. + Completion of scientific investigations with minimal oversight. + Cooperative preparation of technical documents and reports supported with corroborating evidence. + Documentation of laboratory experiments and curation of all associated raw data. + Routine demonstration of scientific creativity and productivity. + Maintains awareness of emerging technology and current best practices. **Teamwork/Customer Relations Responsibilities:** + Identifies and responds appropriately to both internal and external customer needs utilizing available resources. + Collaborates to problem solve and make decisions to achieve desired outcomes. + Establishes effective working relationships with cross-functional team(s). + Responds timely, effectively and appropriately to deliverables. + Shares knowledge, time, and expertise to assist other members of the team. **Educational Requirements:** + Bachelor of Science in analytical chemistry or related science/engineering field required + Master's degree preferred **Experience:** + Three (3) years experience in an industrial or clinical laboratory setting Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

Categories

Posted: 2019-11-15 Expires: 2020-02-02

Before you go...

Our free job seeker tools include alerts for new jobs, saving your favorites, optimized job matching, and more! Just enter your email below.

Share this job:

Bioanalytical Development Specialist - Precision Biomarker Labs

Cedars-Sinai Medical Center
Los Angeles, CA 90006

Join us to start saving your Favorite Jobs!

Sign In Create Account
Powered ByCareerCast