1+ months

Sr. Associate Scientist - Protein Chemistry

Thousand Oaks, CA 91360
  • Job Code

Job ID: R-98556
Location: Thousand Oaks, CA, US 91360

The Amgen Biologics Optimization group is seeking a highly motivated Senior Associate Scientist to join the Protein Chemistry group at our state-of-the-art research facility in Thousand Oaks, CA. The Biologics Optimization group is responsible for the optimization, production, assessment, and selection of large molecule therapeutic drug candidates, many of which are complex biologics.

The Protein Chemistry group is primarily responsible for the purification and analytical assessment of novel and complex scaffold molecules, often antibody-based, that will be the next generation of large molecules therapeutics. The Sr. Associate Scientist will be a part of a multidisciplinary team with capabilities in protein engineering, purification and characterization of large molecule drug candidates with a heavy focus on purification and characterization.

The successful candidate will apply their scientific expertise to assist in the identification and optimization of promising therapeutic candidates to treat serious illnesses and advance Amgen's mission to serve patients.

In our mission to serve patients, speed is absolutely critical. We're rapidly expanding our hiring initiatives and are excited to unite with the most passionate and forward thinking scientific minds who want to join our team - working toward our mission of advancing high potential programs for cancer patients around the world.

Key Responsibilities include:
  • Apply protein biochemistry expertise to purify and analyze therapeutic drug candidates.
  • Drive innovation through the development of novel processes that increase capabilities, speed, throughput and/or quality.
  • Generate scientific data to support generation of publications, patents, or regulatory submissions; participate in internal and external scientific outreach.

Basic Qualifications

Master's degree and 3 years of scientific experience


Bachelor's degree and 5 years of experience

Preferred Qualifications
  • Doctorate degree
  • Experience with protein purification, preferably with complex, engineered large molecules
  • Proficiency with a variety of chromatography techniques (Affinity, IEX, HIC, RP, MMC), liquid chromatography instrumentation (FPLC, HPLC) and software (Unicorn, ChromLab)
  • Familiarity with protein analytical techniques (HPLC, MCE, etc) and analysis software (Chromeleon, LabChip)
  • Knowledge of high throughput purification and analytical techniques is a plus
  • Ability to multi-task, work flexibly and efficiently in a cross-functional environment
  • Strong communication and interpersonal skills; demonstrated ability to analyze and interpret scientific results

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.



Posted: 2020-04-23 Expires: 2020-05-24

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Sr. Associate Scientist - Protein Chemistry

Thousand Oaks, CA 91360

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