30 days old

Scientist 1, Biology (Metabolic Engineering)

Amyris, Inc.
Emeryville, CA 94608
  • Job Code
    120786109


Amyris, Inc.

Location: Emeryville, CA
Team: Research and Development - Biology /
Work Type: Full-Time


Amyris, a leader in industrial synthetic biology, uses its innovative bioscience solutions to achieve renewable products by converting plant sugars into hydrocarbon molecules. Amyris molecules are used in wide range of specialty & performance chemicals, flavors & fragrances and in applications ranging from cosmetics to biofuels. Learn more at www.amyris.com.

As a VEVRAA Federal Contractor, Amyris is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. Amyris complies with applicable state and local laws governing nondiscrimination in employment.

For a full list of our current openings, please visit our website www.amyris.com.

At Amyris, we develop custom microbes and associated processes that transform renewable, plant-based sugars into pure high-value molecules through industrial-scale fermentation. Our technology provides a sustainable alternative to traditional chemical manufacturing and delivers products that directly benefit millions of lives. Our team has developed tailored microbes for the successful scale-up and manufacture of 10 fermentation products in the past 10 years. This track record of product delivery is one of the many advantages that distinguish Amyris from other companies in the sector. We are a team of pragmatic idealists who are using breakthrough science to deliver sustainable solutions for a growing world.

Amyris seeks an energetic, curious, rigorous, collaborative, and self-motivated scientist with a strong background in metabolic engineering, microbial quantitative physiology, and/or synthetic biology to join our Biology team. We are searching for a Scientist to drive metabolic engineering of microbes using the world's most advanced high-throughput automated strain engineering and testing platform. This Scientist will optimize microbes for industrial fermentations to produce small molecules from renewable sugars. Research at Amyris is driven by synergistic collaboration between life sciences and engineering disciplines to accelerate projects from concept to market. We favor candidates who thrive in collaborative, team-oriented environments and are passionate about the Amyris mission.

Responsibilites
    • Design, build, and test microbial strains and enzymes to improve strain performance in industrial fermentations
    • Apply state-of-the-art metabolic engineering approaches and develop powerful novel approaches
    • Generate new hypotheses by mining scientific literature and in-house data and models
    • Design and execute experiments to test hypotheses, thereby removing barriers to high strain performance
    • Employ rational (hypothesis-based) and random (evolutionary) approaches to improve strains
    • Collaborate with researchers in automated strain engineering, high-throughput screening, analytical chemistry, bioinformatics, fermentation, and process development groups to achieve project milestones
    • Analyze diverse data streams via standard statistical analyses, modeling, and collaboration with bioinformatics/
    • AI/ML group to deepen human and machine learning from large datasets
    • Communicate plans, rationales, results, and conclusions to diverse audiences, both verbally and in writing
    • Maintain safe practices and work environment
    • Mentor and train more junior researchers




Qualifications
    • Ph.D. (or equivalent experience) in (bio)chemical engineering, biochemistry, metabolic engineering, microbiology, molecular biology, industrial biotechnology, natural products chemistry, or a related field
    • Prefer candidates with demonstrated track record of successfully introducing and optimizing new metabolic pathways into a microbial host organism and/or interrogating and quantifying metabolic activity in microbes
    • Previous experience in the field of microbial genome engineering and/or synthetic biology is a plus




Experience and competency in several of the following areas:
    • Cellular processes involved in small molecule production, including redox balance, energetics, product transport, growth rate dependencies, fermentation conditions, overflow metabolism, etc.
    • Construction and analysis of models of quantitative cellular physiology and metabolism of microbes or plants
    • Small-scale fermentation processes and principles
    • Gene discovery for particular enzymatic reactions via sequence diversity searches and testing
    • Design and analysis of metabolomics, proteomics, or transcriptomics experiments
    • Molecular biology techniques including PCR, DNA assembly, genome engineering, plasmid construction, DNA sequence analysis, nuclease-triggered DNA recombination, microbial transformation (in bacteria, yeasts, or filamentous fungi), and next gen sequencing
    • Statistics and tools to analyze and visualize data (e.g., Excel, Minitab, R, Spotfire, JMP, Python)
    • Collaboration and teamwork in cross-disciplinary teams


#LI-DJ1



Under the California Consumer Privacy Act of 2018 (CCPA), Amyris is required to inform California residents who are our job applicants (Applicants) about the personal information we collect about you when you apply to a job on this site.

As an Applicant, you have the right to know and understand the categories of personal information we collect about you, and the purposes for which the categories of personal information shall be used, pursuant to the CCPA.

By clicking the APPLY FOR THIS JOB button below and submitting your job application, you agree you have reviewed the complete Privacy Notice for Employees, Independent Contractors and Job Applicants<

If you have any questions regarding this information, please contact Amyris at
privacy@amyris.com

As a VEVRAA Federal Contractor, Amyris is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. Amyris complies with applicable state and local laws governing nondiscrimination in employment.

If you are a recruiter or placement agency, please do not submit resumes to any person or email address at Amyris, Inc. prior to having a signed agreement. Amyris is not liable for and will not pay placement fees for candidates submitted by any agency other than its approved recruitment partners. Furthermore, any resumes sent to us without an agreement in place will be considered your company's gift to Amyris and may be forwarded to our recruiters for their attention.



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Posted: 2020-06-11 Expires: 2020-07-12

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Scientist 1, Biology (Metabolic Engineering)

Amyris, Inc.
Emeryville, CA 94608

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