About the Job The Department of Neurosurgery at the University of Minnesota invites applications for a Research Associate position from candidates with a Ph.D or equivalent degree. The laboratory directed by Dr. Clark C. Chen, M.D., Ph.D., is seeking outstanding scientists who are interested in working in a NIH-funded research program studying the role of non-coding RNA in glioblastoma pathogenesis.
The Department of Neurosurgery at the University of Minnesota is a well-balanced program with significant achievements in teaching, clinical programs and research. The University of Minnesota is one of the highest ranked public universities in research. The successful applicant will receive training in, and be expected to participate in the design, implementation and evaluation of experiments related to on-going NIH funded research. The University of Minnesota shall provide equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.
The ideal candidate should have experience in the studies of non-coding RNAs, including the identification up-stream and down-stream regulatory mechanisms. The candidate should have expertise in standard techniques in the field of non-coding RNAs, including ChIP, CHIP-seq, biotinylated ncRNA pull-down, target read-out assays, and murine xenograft models pertinent to the studies of ncRNA. The candidate should also have experience in the interrogation of The Cancer Genome Atlas (TCGA) ncRNA dataset as well as training in the handling of clinical tumor specimens and bio-fluids derived from human subjects. The candidate must have the ability to define research questions and develop experiment designs to address those questions. The ideal candidate should have experience with brain tumor research, including primary and metastatic brain tumors. The candidate should have experience presenting research results through publications and presentations.
Duties and Responsibilities:
originate research ideas
develop research questions
create research designs
write manuscripts for publications
supervise, as needed, undergraduate, graduate students, junior scientists and postdocs working on related research projects
seek funding opportunities and write grant proposals (e.g. NIH funding)
PhD in biology, biochemistry, molecular biology, cancer biology, or related science field
Expertise in cellular and molecular biology techniques,
Excellent interpersonal skills and ability to work collaboratively with others.
Excellent oral and written communication skills
Experience working with clinical tumor specimens
Experience in murine intrancranial tumor models
Experience working with microRNAs, LncRNA, and circular RNA
Experience in bio-informatic analysis of TCGA database,
Experience with immunohistochemistry
Experience statistical analysis of experimental data
Experience with grant writing
Record of presenting research results through publications and conference abstracts
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.