The Neul lab is seeking a motivated and experienced staff scientist to work closely with Dr. Neul to conduct research and prepare manuscripts and grants. The Neul lab focuses on disease models of neurodevelopmental disorders, with a specific focus on Rett syndrome. The lab uses a variety of techniques including molecular biology, modern genetics, cell culture, electrophysiology, and whole animal phenotyping to evaluate cellular and animal disease models to discover pathogenic mechanisms and develop novel therapies for these disorders.
A successful staff scientist will assist the Principal Investigator with grant and manuscript preparation. Independently carry out and design highly sophisticated and independent experiments. Mentor and train graduate students and post doctoral fellow in developing their research projects.
Important technical skills:
Well-established understanding of genetics, especially mouse genetics
Experience in mouse colony maintenance and breeding
Experience in molecular and cellular neuroscience
Experience in whole animal phenotyping including rodent behavior and physiological assessment
Experience with animal surgeries
Experience with cell culture, especially culturing stem cells and differentiating to neuronal lineages
Strong molecular biology skills
Experience in histology and microscopy, including confocal
Strong quantitative skills and ability to manage and analyze complex large data sets using a variety of computer programs such as Excel, Access, FileMaker Pro, SPSS, R, Matlab, and Python programming
High level proficiency in written English
Key Funcations and Expected Performances
Independently oversee research projects and perform near to totally independent research.
Supervise, plan, design and implement research projects
o Establish highly complex protocol(s); define data collection, evaluation and analysis procedures
Supervise scientific data collection and analyses for research project(s) requiring independent interpretation of complex research data
Exercise discretion and independent judgment to develop methods and procedures for operation of complex scientific equipment
Supervise set-up and operation of various scientific experiments involving complex apparatus and equipment
Contribute to research so as to merit serving as author or co-author on research publications, etc.
Assist principal investigator in writing research grants and contract proposals
Assists PI in manuscript preparation for scientific journals.
Present research findings as needed
Responsible for plan and coordination of literature and library searches and data collection programs
Develop reports of results, graphs, charts, tables, etc. of research findings
Supervise writing, reviewing and editing of various materials for publication
Provide supervisory responsibility to staff
Mentor and teach graduate students and post doctoral fellows in developing their projects and on specific techniques and protocols.
Train and supervise technical staff, medical and graduate students
Provide technical guidance to students, pos-doctoral fellows and faculty as required
May provide budget responsibility
Make recommendations to principal investigator regarding staff, supply and equipment needs for research projects
May monitor expenditures of funds
Maintain open communication between department and others
Open contact as needed with principal investigator, collaborating professionals, Purchasing, Human Resource Services, Space and Facilities Planning, asset management personnel, Environmental Health and Safety, Institutional Review Board staff, administrative staff relating to budget capabilities
Contact as required with sponsoring agencies and/or cooperating facilities (e.g. V.A.), collaborating professionals and vendors
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