At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes.
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We are looking for a Research Technician or Senior Research Technician to provide technical support for the Structural Biology lab. The lab is interested in developing a new generation of optical imaging technologies to enable advances in two hitherto difficult-to-investigate areas: the real-time analysis of macromolecular interactions and motions at the nanometer scale in vivo and the three-dimensional architecture of complex molecular machines.
An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding
Adept at planning and prioritizing work to meet commitments with a keen eye for detail
Action oriented and eager to take on new opportunities and tough challenges with a sense of urgency, high energy, and enthusiasm
Familiar with gene targeting techniques, preferably in mice
Prepare mammalian nuclear factors, including recombinant proteins produced in bacteria and insect cells, as well as native large macromolecular complexes from human cells
Assay purify proteins using in vitro transcription assays, native gel electrophoresis, DNAse I and permanganate footprinting
Design, clone, and assay constructs for various genes of interest using standard molecular and cell biology techniques (PCR, transformation, cloning, subcloning, DNA/RNA miniprep and maxiprep, Western and Northern blotting, etc.)
Be responsible for cell culture procedures, including large-scale growth of mammalian cells in suspension and of mouse embryonic stem cells
Ensure stocks of lab supplies are maintained, place orders as necessary, maintain lab equipment and perform other duties as assigned
BA/BS in biological sciences with a minimum of 1-3 years research experience. Master's degree highly preferred.
Strong technical ability in molecular/cell biology and biochemistry required
Previous protein purification experience preferably with endogenous nuclear complexes
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
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As one of the world's premier cancer centers, Memorial Sloan-Kettering Cancer Center is committed to exceptional patient care, leading-edge research, a...nd superb educational programs. The close collaboration between our physicians and scientists is one of our unique strengths, enabling us to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future. Our education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan-Kettering has an impact on cancer treatment and the biomedical research agenda around the world.