DEPARTMENT MISSION AND BACKGROUND INFORMATION The Mass Spectrometry and Proteomics Facility is a Biotechnology Resource Center service facility that provides fee-for-service access to advanced technologies in protein and small molecule identification and characterization through Liquid Chromatographic Mass Spectrometry. Customers of the facility include faculty, researchers, staff and students from Cornell University, Weill Medical College, and external non-profit and for-profit institutions. The position will be part of a high-energy, cutting-edge Proteomics and Mass Spectrometry Facility team and requires the ability to participate in multi-disciplinary research in a collaborative setting.
This position will assist the Director of the Proteomics and Mass Spectrometry Core Facility in the development and implementation of various sample preparation techniques and LC-/MS/MS techniques for metabolomics analysis, and subsequent MS data interpretation. The incumbent in this position is primarily responsible for LC-MS/MS analyses on a variety of samples prepared from complex biological sources, operation and maintenance of an advanced HPLC and electrospray mass spectrometric instruments, as well as several untargeted metabolomics-based database search engines and bioinformatics tools. The incumbent will need a strong organic chemistry background, and have significant knowledge of small molecule/drug metabolism with basic metabolic reactions, and MS-associated bioinformatics tools for untargeted metabolomics profiling and identifications. The incumbent will need to possess excellent MS data interpretation skills towards interpretation of mass spectra for structural elucidation, and be able to routinely perform post-MS analysis data interpretation for customers. The incumbent in this position will be required to develop standard operating and quality assurance procedures covering sample preparation and multiple LC separation technology for variable metabolomics samples, and to provide consultation on metabolomics project design and data analysis.
The incumbent will be required to write a variety of technical and/or project reports to the facility users and collaborative PIs. The incumbent is expected to contribute to the preparation of publications and grant proposals. Strong oral and written communication skills are required. In addition, the incumbent is required to keep a detailed laboratory notebook, contribute to general orderliness of the laboratory and support lab health and safety compliance.
This position is a three-year term appointment with the possibility of extension contingent upon continued funding.
* PhD degree in Biochemistry, Chemistry, Biology or related discipline
* At least three years LC-MS experience on metabolomics research required
* Must possess a strong work ethic and self-motivation
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