Salary is commensurate with experience and education
The University of Washington (UW) is proud to be one of the nation's premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement, artistic pursuits, and natural beauty.
The Division of Dermatology is one of 14 subspecialty Divisions in the Department of Medicine. The mission of the Dermatology Division is to provide outstanding patient care, train and mentor future leaders in dermatology and advance dermatologic knowledge. The Dermatology Division is affiliated with University of Washington Medical Center, Seattle Cancer Care Alliance, Harborview Medical Center, Children's Hospital and Regional Medical Center and VA Puget Sound Health Care System. There are two postdoctoral training programs in Dermatology, Dermatology Residency Program and Procedural Dermatology Fellowship Program. Dermatology faculty conduct basic research and clinical trials, provide patient care and participate in the training of medical students, residents and fellows.
The UW School of Medicine, Division of Dermatology has an opening for a Research Scientist / Engineer 2 in the laboratory of Dr. Paul Nghiem. The Nghiem Lab (UW Medicine South Lake Union; pnlab.org) is a moderately sized, diverse lab with basic, translational, and clinical research projects. A major focus for the lab is Merkel cell carcinoma, an uncommon but frequently lethal skin cancer associated with immune suppression, UV exposure, and the Merkel cell polyomavirus (see www.merkelcell.org). Due to our location in South Lake Union, there is opportunity for participation in the fast paced and exciting immunotherapy research community thriving in the area.
Under the direction of the Principle Investigator and senior laboratory scientists, the successful candidate will expand the knowledge of cancer immune correlates in MCC patients by exploiting our unique Merkel cell carcinoma specimen repository that includes fresh tumor tissue, preserved tumor tissue, blood and serum in combination with patient outcomes and clinical information.
Responsibilities and Duties
Process and preserve human tumor tissue and biological specimens (serum and peripheral blood mononuclear cells) for studying Merkel cell carcinoma specific T cell responses.
Receive, organize and track data from outside labs (both clinical and research labs) and enter into a relational database for use in Merkel cell carcinoma patient studies.
Assist in experimental method development and optimization to measure the T cell response to Merkel cell carcinoma and correlate to patient specific outcomes.
Use a bacterial based protein expression system to generate reagents used in a serological assay to detect and measure the oncoprotein antibody response to Merkel cell carcinoma.
Use Western blot, Bradford assays and Coomassie stain to quantitate protein concentrations of preparations and cell lysates.
Maintain laboratory inventory of commonly used reagents and order new items as needed.
Analyze, organize and present experimental results at lab meetings and conferences.
Generate graphs and figures for contribution to manuscripts for publication as well as grant applications.
This position requires a self-motivated and detail-oriented individual who is eager to engage with a multi-disciplinary team in basic and translational research. We believe this position will serve as superb training in translational research and tumor immunology. There are opportunities for direct patient interaction and patient samples will be associated with outcomes/molecular studies.
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Bachelor's degree in Biology, Biochemistry, Microbiology or related Life Sciences field plus a minimum of1-2 year's experience working in a laboratory setting.
Experience and knowledge of the fundamental concepts, practices and procedures required for working in a research laboratory.
Able to work independently and as part of a multidisciplinary team.
Willing to learn new techniques.
Self-motivated with the ability to take initiative and work independently.
Excellent communication skills and very high level of attention to detail.
Ability to commit to a minimum of 2 years.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
CONDITION OF EMPLOYMENT:
Appointment to this position is contingent upon obtaining satisfactory results from a criminal background check.
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Criminal Conviction History, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select Apply to this position. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your My Jobs page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergra...duate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.