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The Pavletich lab is interested in the structural biology of pathways that are altered in cancer, with particular emphasis on pathways that control the growth and proliferation of the cell. In cancer, mutations and other alterations in these pathways lead to the uncoupling of cell growth from growth-regulatory signals and contribute to the unrestricted proliferation of the tumor cell.
We are looking for a Research Technician or Senior Research Technicianthat works with a postdoctoral associate on structural and biochemical studies of cancer-related proteins and protein complexes. Work involves the cloning, overexpression and purification of proteins from prokaryotic and eukaryotic cells, and functional studies by in vitro biochemistry and by X-ray crystallography.
Prepares laboratory equipment, instruments, solutions, stains, assays and other supplies as instructed for research experiments.
Work may involve culture and/or cell separation methods; electrophoretic separations: assays (e.g., RIA, TIA, ELISA); basic biology or other specialized science techniques depending on the lab.
Operates lab equipment such as centrifuges, pH meters, analytical balancers, scintillation counters, spectrophotometers, light microscopes and other equipment as instructed.
May be involved in animal handling requiring injection of animals, collection/harvesting of tissues, fluids; animal autopsies in order to make chemical identification and conduct analyses.
Responds to and completes tasks as instructed by the P.I. and staff associated with designated research projects by carrying out the requested activities.
For Research Technician level, a Bachelor's in Biology or closely related major with 0-3 years related experience.
For Senior Research Technician level, a Bachelor's in Biology or closely related major with 3+ years related experience or Master's with at least 1 year of related experience
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
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As one of the world's premier cancer centers, Memorial Sloan-Kettering Cancer Center is committed to exceptional patient care, leading-edge research, a...nd superb educational programs. The close collaboration between our physicians and scientists is one of our unique strengths, enabling us to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future. Our education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan-Kettering has an impact on cancer treatment and the biomedical research agenda around the world.