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The Pavletich lab is interested in the structural biology of pathways that are altered in cancer, with particular emphasis on pathways that control the growth and proliferation of the cell. In cancer, mutations and other alterations in these pathways lead to the uncoupling of cell growth from growth-regulatory signals and contribute to the unrestricted proliferation of the tumor cell.
In this role, the Research Technician or Senior Research Technician works with a postdoctoral associate on structural and biochemical studies of cancer-related proteins and protein complexes. Work involves the cloning, overexpression and purification of proteins from prokaryotic and eukaryotic cells, and functional studies by in vitro biochemistry and by X-ray crystallography.
For Research Technician level, a Bachelor's in Biology or closely related major with 0-3 years related experience.
For Senior Research Technician level, a Bachelor's in Biology or closely related major with 3+ years related experience or Master's with at least 1 year of related experience.
Knowledge of basic biochemistry and molecular biology methods required. Laboratory experience with protein purification, enzyme assay development, or eukaryotic cell culture preferred.
Hours: 9:00am – 5:00pm. Monday – Friday
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As one of the world's premier cancer centers, Memorial Sloan-Kettering Cancer Center is committed to exceptional patient care, leading-edge research, a...nd superb educational programs. The close collaboration between our physicians and scientists is one of our unique strengths, enabling us to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future. Our education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan-Kettering has an impact on cancer treatment and the biomedical research agenda around the world.