Post-doctoral position in Neurophysiology to study thalamocortical and midbrain circuits involved in sensorimotor information processing during behavior. The lab investigates how neural circuits dynamically change their activity and sensory responsiveness during different behavioral states in mice. We are interested in deciphering the neural mechanisms by which the significance of sensory stimuli is modified through experience -particularly in the context of active avoidance conditioning. The successful candidate will employ electrophysiological recordings, together with optogenetics and DREADDs, in freely behaving rodents and in vitro (slices of brain tissue) to study the regulation of neural activity in these circuits during behavior. The lab will provide access to an assortment of electrophysiological, imaging, optogenetic, neurochemical, histological and behavioral procedures. Experience with some of these procedures is highly desirable.
For more info:
Prof. Manuel Castro-Alamancos, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia PA 19129