Salary is commensurate with education and experience
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our Benefits page.
The University of Washington (UW) is proud to be one of the nation's premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement, artistic pursuits, and natural beauty.
The UW Department of Otolaryngology Head and Neck Surgery prides itself in offering compassionate, state of the art patient care alongside comprehensive teaching, training and research in the broad areas of disorders affecting the organs of communication.
Our faculty practice at the region's top facilities, including the UW Medical Center, UW Medicine Eastside Specialty Clinic and Seattle Children's Hospital. Our researchers are exploring and investigating a wide variety of topics, including molecular and genetic profiles of oral cavity cancer, and vascular and lymphatic malformations. And our staff, residents, fellows and friends are committed to carrying out our mission to provide excellence and leadership in all aspects of Otolaryngology - Head and Neck Surgery.
The Department of Otolaryngology - Head and Neck Surgery currently has an outstanding opportunity for a RESEARCH SCIENTIST/ENGINEER 4. Working under the general direction of a Principal Investigator(s), this position will study the genes that cause disease progression in head and neck cancers. This person will run in vitro (cell line) assays and conduct animal studies to test experimental manipulations of genes of interest. This person will also help the PI with managerial duties to maintain lab infrastructure.
FUNCTIONS AND RESPONSIBILITIES:
I. Laboratory Duties:
1. Perform basic research in human cell lines and human tissue to discover genes associated with head and neck cancer metastasis. Specifically, candidate will test phenotypic endpoint on cell lines such as viability, apoptosis, metastatic potential, etc., after genome-wide gene knock-down screens and drug screens. Candidate genes will be selected for in vitro and in vivo validation. 2. Perform studies on mice bearing head and neck cancer xenografts to test hypothesis of candidate genes of interest in in-vivo models. This will also include maintaining IACUC protocols. 3. Maintain head and neck tumor repository from consented patients. This will include cataloguing samples, cryopreservation, and generation of primary cell cultures when applicable from samples collects. 4. Independently apply problem solving techniques. 5. Develop extensions to existing methods. 6. Supervise Research Technologist Staff.
II. Administrative Responsibilities:
1. Develop and maintain relationships with grant sponsors and investigators of external research to identify and develop new funding sources; identify grant/project extensions. 2. Initiate new project concepts 3. Develop technical proposals and makes presentations to the PI and collaborators. 2. Implement development of projects and direct/participate in major proposal preparation and presentations. 3. Chair sessions at technical meetings. 4. Perform related duties as required.
PhD in molecular/cell biology or equivalent,and a minimum of four years experience training and working with p53 genes, WEE1-inhibitors, and vertebrates in an experimental situation including but not limited to gene-knockout mice.
Possess bioinformatics skills and have ability to perform data analysis using commonly available statistical and database softwares.
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Criminal Conviction History, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select Apply to this position. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your My Jobs page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
CONDITION OF EMPLOYMENT:
At times of high productivity or experimental deadlines, additional evening, morning, and weekend hours will be required.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergra...duate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.