The Stanford Institute for Stem cell Biology and Regenerative Medicine is seeking a Life Science Research Assistant (LSRA 1) to support cancer research projects in a cell and molecular biology lab. The LSRA will be primarily responsible for conducting in vivo experiments and the following tasks: (1) to process solid tumor and non-tumor specimens the duty includes obtaining human specimens from the clinic, purifying cells and cryopreservation, and thawing and processing of cells for experiments; (2) to assay tumor specimens for engraftment the duty includes transplantation of solid tumor cells into mice, and subsequent biological assessments, such as bio-luminescence imaging; (3) to conduct treatment experiments on tumor-engrafted mice with candidate therapeutics the duty includes administering candidate therapeutics to mice per schedule and assessing effect on tumor engraftment; (4) to manage the mouse colony the duty includes monitoring the tumor-engrafted animals by observing their general condition and maintaining inventory of mouse strains and breeding. The candidate will support defined projects and will be assigned a portion of the projects to handle independently, thus expected to be extremely organized and manage time efficiently. The position also entails lab management support such as ordering supplies and equipment, maintaining lab records, and adhering to safety regulations.
The successful applicant will have a Bachelors degree in Biology or Biological Sciences. Two years of experience and comprehensive understanding of biological sciences principles The successful applicant will have experience working with rodents. The successful applicant will have experience in basic tissue culturing and sterile technique. The successful applicant must be able to adjust to an occasional flexible work schedule during weekdays when human specimens become available from the hospital and clinics. The successful applicant will have efficient communication and interpersonal skills as well as willingness to follow instruction and protocol strictly and to work meticulously with attention to detail. The successful applicant will have general computer skills and the ability to quickly learn and master computer programs for record keeping is essential. The successful applicant will have strong analytical skills and excellent judgment. It is essential that the successful applicant have the ability to work under deadlines with general guidance. The successful applicant will be expected to understand and observe the university policy of working with human specimens and animals.
Desired Qualifications: It is desired that the applicant have the ability to operate IVIS Spectrum and analyze data using Living Image software. It is desired that the applicant have experience with tumor xenograft mouse models. It is desired that the applicant have experience with basic biomethods on mice, such as handling (i.e restraint, ear notch, clinical observations, body weights, tail tipping), dosing (i.e. PO, SC,IP, IV), blood collection
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