Life Science Research Professional 1 - 70712
Description The Human Immune Monitoring Center at Stanford University is seeking a highly motivated Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments. Our understanding of the immune systems ability to combat infection and disease is broadening with the development of new cutting-edge technologies and diagnostics that will help answer questions across the clinical landscape. The Human Immune Monitoring Center is dedicated to the discovery of novel cellular pathways and biomarkers that have the potential to be targeted for diagnostic and therapeutic development. Areas such as cancer immunotherapy and stem cell therapy are now making headlines globally, thanks in part to the development of technologies that help us monitor and activate the immune system.
The LSRP1 will perform basic functions and activities involved in defined research projects, which principally involve purification and characterization of human biospecimen derivatives, from both biofluids and tissue/tumors, to better understand protein expression. Generation of single-cell suspensions, enrichment of targeted CD45+ cell subsets, and immunophenotyping of extracellular and intracellular proteins by CyTOF, targeted RNA sequencing, immunoassays, and flow cytometry, are just some of the applied downstream applications for understanding the biospecimens. While some limited degree of on the job training is acceptable for desired areas, this will be determined on a case by case basis and depend on the additional skill sets the candidate possesses. The LSRP1 is expected to independently conduct, analyze, and present experiments under the support and guidance of faculty investigators, postdoctoral fellows, and other leadership in the center.
* - Other duties may also be assigned
- Plan and perform experiments in support of research projects in lab and/or field based on knowledge of scientific theory. Interpret and perform basic analyses of results.
- Isolation, expression, and purification of human CD45+ cells from whole blood and tissue/tumors.
- Evaluation of targeted surface and intracellular antigens via immunoassays, genomic expression analysis (both RNA and DNA), flow cytometry, and CyTOF.
- Review literature on an ongoing basis to remain current with new procedures and related research.
- Offer suggestions regarding modifications to procedures and protocols in collaboration with faculty investigators and other labs.
- Maintain detailed records of experiments and outcomes.
- Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- Help orient and train new staff or students.
Qualifications DESIRED QUALIFICATIONS:
EDUCATION & EXPERIENCE (REQUIRED):
- Degree in Biology, Molecular Biology, Biochemistry or related field
- Proficiency in molecular biology or immunology
- Highly motivated, dedicated, and independent
- Strong team player
- Excellent written and oral communication skills
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
CERTIFICATIONS & LICENSES:
- General understanding of scientific principles.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
* - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
Location: School of Medicine
Job Code: 4951