| Summary Description: Dr. Chaolin Zhang laboratory at Columbia University Medical Center is seeking a motivated Staff Associate to support ongoing studies of RNA regulatory circuitry in the mammalian nervous system. The Zhang laboratory is a newly formed lab in the Department of Biochemistry and Molecular Biophysics (BMB), the Columbia Initiative in Systems Biology (CISB), the Center for Motor Neuron Biology and Disease (MNC), and the Columbia Stem Cell Initiative (CSCI). Using a combination of biochemistry, molecular biology, and high-throughput quantitative and integrative approaches, the Zhang Laboratory studies how proteins and RNA interact to form regulatory networks in the nervous system at the mechanistic and systems level. These networks are increasingly shown to be essential to understand the mammalian complexity manifested in evolutionary-developmental (evo-devo) processes and in neuronal disorders. The successful candidate will join a vibrant, interdisciplinary and productive research team, and would work closely with the principal investigator, post docs, and graduate students in designing, carrying out, and coordinating research. More information about the Zhang laboratory can be found at http://zhanglab.c2b2.columbia.edu.|
Minimum Qualifications: A Bachelor/Master degree in a biological science or related subject area.2) Exceptional skills in molecular biology and biochemistry (e.g., cloning, mutagenesis, IP/CoIP, western, IHC, RNAi, etc)3) Extensive experience in mammalian tissue culture and mouse models4) Ability to plan and design projects independently as well as to collaborate in a group setting. 5) Great organizational and time management skills6) Superior written and verbal communication skills, with the ability to train personnel and clearly communicate scientific objectives and project results7) Ability to oversee equipment procurement and maintenance.8) Ability to oversee day to day activities in the lab, including supervising ordering of supplies, developing and implementing standard operating procedures, and supervising lab members on lab safety and compliance.
Preferred Qualifications: Experience with high-throughput sequencing technology/analysis, and microarray experiments/analysis. Experience with stem-cell biology, including iPS neration and iPS/mESC differentiationBasic bioinformatics knowledge and programming.
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Columbia University is an Equal Opportunity/Affirmative Action employer.