Senior Research Scientist - Institute for Systems Genetics
NYU Langone Health
March 10, 2018
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We have an exciting opportunity to join our team as a Sr Research Scientist.
Position available for a Senior Research Scientist with strong computational skills and management experience. The Noyes lab (www.noyeslab.com) is growing and as we expand our work we need a strong computationalist to handle initial data analysis and to better interface with our collaborators. As students join the lab with computational interests, this person will be relied upon to mentor these students for their computational tasks. In addition, this position will handle some day to day function of the lab. I am looking for my right hand person on the bioinformatic side of our research that can be the go to person in the lab when I am unavailable.
The Noyes lab in the Institute for Systems Genetics at the NYU School of Medicine is looking to build a team of exciting young scientists to scale up our understanding of protein interacts. At the heart of what we do is understanding the nuts and bolts of the molecular interactions between proteins and their targets. Our ultimate goals are first to characterize these interactions, the influence of genetic variation, and the connection to phenotype; but we also want to use this information to develop molecular, therapeutic tools that manipulate these interaction and the genomes that harbor them. We have already begun to put together a talented group and have been awarded funding from the NIH to support these projects. Our general focus can be summed by these themes: Understanding how proteins determine target preference, with particular interest in low affinity interactions. Describing the influence genomic variation has on protein function. The development of novel genome manipulating tools (CRISPR, ZFN, pathway inhibitors) for precise applications such as of therapeutic gene repair and cancer suppression.
Demonstrates knowledge of the organizations Core Values and incorporates them into the performance of duties.
Initiates, interprets, organizes, executes, and coordinates research assignments critical to departments mission.
Formulates and conducts research on problems of considerable scope and complexity.
Explores subject area and defines scope and selection of problems for investigation through conceptually related studies or series of projects of lesser scope.
Makes decisions and recommendations that have a major impact on extensive scientific research activities.
Develops new ideas that promote current research. Exercises a high degree of creativity, foresight, and mature judgment in planning, organizing, and guiding extensive scientific research programs and activities of outstanding novelty and/or importance.
May manage the operations of a lab for the Principal Investigator by supervising Post Docs and technicians. Oversees the maintenance and upkeep of all instruments and laboratory facilities.
Ensures timely and accurate completion of research projects.
May provide students with technical guidance and direction in the operation of various techniques and equipment as well as general laboratory practices and safety protocols.
May seek grant funding from external sources in support of their independent research projects with consent of the PI and the Department Chair. May participate in writing grant proposals.
May be responsible for research/lab quality control and compliance.
May develop protocol for the collection and quality of research data.
Develops research techniques and methodologies.
May determine and establish laboratory policies, procedures and practices.
Maintains a thorough knowledge of the advances in specialized fields through attendance of scientific conferences.
May make significant contributions to scientific papers. Is a resource/ author/ co-author for reports and presentations.
May provide recommendations for equipment purchases and for the redesign of lab space.
May coordinate the activity and experimental design between various labs, scientific staff, and collaborators. Identifies and resolves technical problems.
Performs other related duties as assigned.
To qualify you must have a MD or PhD. Established a record of publications Candidates will have extensive experience dealing with large data sets, primarily recovered by next-generation sequencing.
An understanding of protein function at the structural level is highly desirable. While extensive wet bench experience is not completely necessary, it would be helpful. If nothing else, the candidate should have the desire to learn this side of the research as these skills will allow for better mentorship of new students. Therefore, experience working with either bacteria and human tissue cultures, cloning, genome editing, protein/nucleic acid library design as well as familiarity with common modes of protein-DNA, protein-RNA or protein-protein interactions, would be desirable.
Qualified candidates must be able to effectively communicate with all levels of the organization.
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Internal Number: 60912372
About NYU Langone Health
NYU Langone Health, a world-class patient-centered integrated academic medical center, is one of the nation's premier centers for excellence in clinical care, biomedical research, and medical education. Located in the heart of Manhattan, NYU Langone is composed of four hospitals – Tisch Hospital, its flagship acute care facility; Rusk Rehabilitation; the Hospital for Joint Diseases, one of only five hospitals in the nation dedicated to orthopaedics and rheumatology; and Hassenfeld Children's Hospital, a comprehensive pediatric hospital supporting a full array of children's health services across the medical center – plus the NYU School of Medicine, which since 1841 has trained thousands of physicians and scientists who have helped to shape the course of medical history. The medical center's tri-fold mission to serve, teach, and discover is achieved 365 days a year through the seamless integration of a culture devoted to excellence in patient care, education and research. For more information, go to www.nyulangone.org.