The Director of the Mouse Transgenic and Gene Targeting Facility at Brown is responsible for the production and delivery of CRISPR-Cas9 generated transgenic mice based on individual project needs as well as the management of the research assistant and day-to-day operations of the core facility whose main focus is providing gene-targeted and transgenic mice. Working directly with the scientific community, faculty on the main campus and the jewelry district and with users at the Brown-affiliated hospitals, the Director generates unique transgenic and gene targeted animals for use, based on specific needs of individual projects. This work primarily requires performing CRISPR-Cas9 targeted gene disruptions and tagged alleles in mouse embryos and ES cells. The facility also provides cryogenic storage services and performs mouse re-derivations and cryo-preservations for the Brown research enterprise. Additional responsibilities include developing and improving techniques and procedures and providing consultative services to the community in the design and implementation of transgenic animals. In addition, the Director will organize the financial records and budgets for the facility, supervise Research Assistants and technical staff, maintain records, and compile, interpret and analyze data. The Director provides overall oversight and management for the facility, its equipment, inventories, and supplies. Working strategically and collaboratively with department leadership, animal care and stakeholders, the Director promotes usage and effectively markets the services provided ensuring continuing growth and usage of the facility.
Bachelorâ™s degree in molecular biology, genetics, biochemistry, or related field (PhD or Masterâ™s degree preferred) with 5-10 yearsâ™ experience in mouse genetics including solid and demonstrated skills in all aspects of transgenic and gene targeted mouse production and specific experience generating gene targeted mice in a BL/6 background (or any equivalent combination of education and experience).
Experience with CRISPR-Cas9 technology preferred.
Excellent organizational, record keeping and report preparation skills
Solid computer skills (Excel, Word, Powerpoint, Explorer)
Ability to analyze data
Experience developing/ and managing a budget as well as projections
Good marketing and business skills
Criminal background and education check required
Recruiting Start Date:
Job Posting Title:
Director, Transgenic Facility
Department of Molecular Biology, Cell Biology and Biochemistry
Fixed Term (Fixed Term)
Scheduled Weekly Hours:
Please note that in order to be considered an applicant for any staff position at Brown University you must submit an application form for each position for which you believe you are qualified. Applications are not kept on file for future positions. Please include a cover letter and resume with each position application.
Brown University is committed to fostering a diverse and inclusive academic global community; as an EEO/AA employer, Brown considers applicants for employment without regard to, and does not discriminate on the basis of, gender, sex, sexual orientation, gender identity, national origin, age, race, protected veteran status, disability, or any other legally protected status.
Internal Number: REQ143117
About Brown University
Located in historic Providence, Rhode Island and founded in 1764, Brown University is the seventh-oldest college in the United States. Brown is an independent, coeducational Ivy League institution comprising undergraduate and graduate programs, plus the Alpert Medical School, School of Engineering, Executive Master of Healthcare Leadership and the IE Brown Executive MBA.