Job Posting: Job Summary: The Research Associate III will join our newly founded clinical – contract research laboratory consortium. Our mission is to develop novel assays that will allow patients to be diagnosed and monitored more accurately and precisely. The Research Associate III will be part of a new Clinical Laboratory R&D team responsible for development and analytical validation of quantitative analytical workflows for use in clinical diagnostics. The quantitative analytical workflows include, but are not limited to, sample preparation and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for small and large molecules (e.g., proteins, peptides and drugs) in various biological matrices. Responsibilities include designing and performing experiments, operating and troubleshooting test equipment, and interpreting and compiling data to ensure optimal method performance meeting requirements for clinical use. The Research Associate III complies with quality and safety requirements, participates in creating and updating SOPs and research protocols, and will keep appropriate experimental records and documentation. Additional duties include general support functions necessary for the routine operation of the laboratory. Performs all job duties with sensitivity and attention to the developmental issues of the patient population(s) being served.
Qualification Requirements/Preferences: Education Certifications/Licensure Experience Physical Abilities Educational Requirements: A Bachelor of Science Degree in analytical chemistry, biochemistry, or related field is required. A Master of Science Degree is preferred. License/Certification/Registration Requirements: N/A Experience: Three to five (3-5) years of experience in area of research specialization. Has technical skills and expertise in an area of study including, but not limited to, r mass spectometry, clinical diagnostics or bioanalysis. Experience with quantitative LC-MS/MS method development and validation, troubleshooting and maintenance of LCMS/MS instruments, and biological sample clean-up using manual and/or automated methods is strongly preferred. Strong computer skills (MS Word, MS Excel, MS Access, PowerPoint). Strong analytical and problem-solving skills; excellent organization skills and very detail-oriented; learns new tasks quickly; self-motivated; works well independently with minimal supervision; works well with others, and able to multitask. Strong interpersonal skills for interaction with peers, patients, physicians, and other customers of the medical center. Thorough technical and theoretical understanding of PI's research objectives. Mastery of complex or unusual technical procedures and protocols. Ability to research, develop and implement new laboratory procedures and protocols. Knowledge of human resource and administration policies and procedures. Knowledge of budgetary requirements and policies. Preferred experience:
Three years of hands-on experience with quantitative LC-MS/MS method development and validation.
Three years of experience with troubleshooting and maintenance of LC-MS/MS instruments.
Knowledge of biological sample clean-up, enrichment and extraction techniques using manual and/or automated methods.
Experience in managing, analyzing, and displaying/reporting large data sets.
Experience with LC-MS/MS acquisition and data-analysis software, e.g., Analyst/MultiQuant (Sciex) or XCalibur/PeakFinder (Thermo) Preferred Skills:
Well-organized with high attention to detail.
Willing and eager to learn new technologies.
Team worker with desire and ability to contribute to patient care-driven research.
Flexible and creative in adapting to different circumstances and expectations.
Highly motivated and able to work independently.
Excellent written and verbal communication skills.
Familiar with Good Laboratory Practices (GLP) and compliance to FDA/CLIA validation requirements.
Ability to adhere to project timelines and deadlines in an evolving and developing laboratory environment Physical Demands: (e.g., lifting, standing, walking) Position requires working with general lab equipment, microscopes and computers for extended periods of time and the use of specialized laboratory equipment. Must be able to sit, stand and/or stoop for long periods of time. Must be able to lift at least 20 pounds.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scien...tists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.