Salary is commensurate with education and experience
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our Benefits page.
As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a Great College to Work For for four consecutive years.
The Department of Immunology has grown to include 33 faculty, ~30 graduate students and more than 70 post-doctoral trainees. We are a strongly interactive group and share the view that the immune system provides an unparalleled platform from which to study processes common to all of mammalian biology, processes unique to host defense, and processes of clear and immediate importance to the understanding and amelioration of human disease.
The Department of Immunology currently has an outstanding opportunity for a RESEARCH SCIENTIST ENGINEER 3.
Research in the Clark laboratory is focused on B cell immune responses to antigens and viruses. Using inbred and conditional knockout strains of mice, the laboratory is investigating how innate immune responses program protective immunity to infections such as from West Nile virus (WNV) and Salmonella typhimurium. The lab is also developing novel immunotherapeutics and vaccines for treating and preventing infections.
1. Manages research projects of moderate size and scope; makes substantial contributions to determining feasibility of goals and objectives. The RS3 works independently with no oversight required and reports significant issues directly to the PI, as necessary. Identifies the need for and creates new research methods and approaches; a major contributor of development strategies and rectifying methodological problems, makes substantial contributions to the scientific findings and implements appropriate procedural modifications utilizing approaches including:
a. Cell culture: He/she applies independent problem solving requiring the application of existing and emerging scientific knowledge to create, monitor and implement effective plans for sterile culture of bacterial, eukaryotic cell lines and primary murine cells; preparation of stably transformed lines; transfections; isotopic labeling; multicolor flow cytometry; confocal microscopy.
b. Molecular genetics and biochemistry: Manage the prepare of DNA from plasmids, cell culture and primary cells; serve as lead in the preparation and analysis of nucleic acid samples by restriction digestion, PCR and other techniques; creates, monitors and implements effective plans for the preparation of DNAs for sequence analysis, genotype cell line, expression and purification of recombinant proteins, immunoprecipitation and Western blot analyses; takes lead in the preparation and purification of monoclonal antibodies and their derivatives.
2. With an expert knowledge of the lab's strategic objectives, the scientist will cultivate and enhance relationships with investigators of external research to identify and develop new funding sources; identifies grant/project extensions such as supplemental funding, needs for no-cost extension of a project and/or fellowships.
3. Present research results at laboratory meetings. Develops technical proposals and makes presentations at national and international conferences and research meetings
4. Contribute materials for grant submissions. May initiate new project concepts and seek funding.
5. Document results routinely and carefully in lab notebooks, prepare results for reports and publications.
6. Interact corroboratively with research team. Successfully manages multiple projects and tasks associated with the Clark lab research. Serves as a mentor and trainer for junior researchers, laboratory staff, and students with the development of advanced research skills and to ensure lab efficiency and project completion. Active member of the hiring team for evaluation and identification of additional staff members.
7. Other duties as assigned such as:
a. Experiments in mice: Handling mouse including intraperitoneal and retro-orbital immunizations; infection of mice with West Nile Virus (WNV) and Salmonella typhimurium and tissue harvesting.
Master's Degree in biological sciences or related field and at least 1 year of experience working in the areas of immunology, biochemistry and/or molecular biology.
PhD in microbiology or immunology and 3 years experience working in the areas of immunology, biochemistry and/or molecular biology desired.
Preference given to someone with experience with antibody engineering, expression and purification of recombinant proteins and/or immunologic methods. Must be willing to work with mice and in a team setting.
Appointment of the successful candidate to this position may be made contingent upon a satisfactory outcome of a criminal conviction history check .
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Criminal Conviction History, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select Apply to this position. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your My Jobs page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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