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The Hauf Lab at Virginia Tech is looking for a highly motivated Postdoctoral Associate in the technical areas of molecular biology, biochemistry or quantitative cell biology. The laboratory works on exciting projects that address the molecular basis of reliable cell division using fission yeast as model organism. We are looking for ambitious, creative and smart colleagues, whose experience enriches our team. Possible projects include: The dissection of the gene expression network underlying mitotic checkpoint signaling. Techniques will include CRISPR/Cas9-mediated genome engineering, single-molecule mRNA FISH, quantitative fluorescence microscopy, and other quantitative molecular biology techniques (e.g., qPCR, ChIP-seq ChEC-seq). A systems analysis of the mitotic checkpoint protein network that addresses how misexpression of checkpoint genes (frequently observed in cancer) impacts the functionality of the checkpoint. Techniques will include yeast genetics, CRISPR/Cas9-mediated genome engineering, quantitative live cell imaging and image analysis, as well as computational modeling. Identifying mechanisms that establish the proper dynamics of mitotic exit. Techniques will include structure-function analysis of single proteins, biochemical in vitro assays, yeast genetics, quantitative live cell imaging and image analysis, and possibly single-molecule in vitro assays.
Ph.D. degree in biochemistry, biology, or a related field; at least one publication in a peer-reviewed journal; demonstrated expertise in at least one of the fields of interest (molecular biology, biochemistry, quantitative cell biology); demonstrated ability to design and troubleshoot experiments; knowledge of the literature in prior fields of study; very good organizational skills and time management; prior experience in supervising others; good communication skills, and the ability to work in a team.
Experience in working with yeast; experience in coding or bioinformatics; demonstrated experience in writing publications.
Employee Category: Research Faculty
Appointment Type: Restricted
Tenure Status: Non-Tenure Track
Percent Employment: Full-time
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