There is currently a postdoctoral research position available in the Department of Pharmacology at the University of Michigan, Ann Arbor, MI. The position is for an NIH-funded research project focused on discovery of novel bioactive metabolites in circulation and their effects on platelet function. Applicants should have successfully defended their PhD thesis and be willing to commit a minimum of 2-3 years to the project as a postdoctoral research fellow. The lab functions in a collaborative work environment with access to all of the state-of-the-art equipment in order to gain a greater understanding of signaling in the platelet, hemostasis and thrombosis in the in vitro, ex vivo, and in vivo setting in both human and mouse models.
Project description: This project will focus on attaining a greater understanding of how fatty acid metabolites generated in the vessel regulate platelet function, hemostasis and thrombosis. The applicant should be familiar with mouse models. The project will involve working with both mouse and human blood samples and platelets. The project will utilize the following equipment located in the lab: 1) intravital microscopy, 2) aggregometry, 3) flow cytometry, 4) western blot electrophoresis, 5) PCR. Additionally many resources are available in the University of Michigan Medical Center including state-of-the-art mass spec facilities, collaborative opportunities with a large community of cardiovascular researchers, and collaborative opportunities with a large community of pharmacology researchers.
Requirements: PhD, MD, or MD/PhD degree. Experience working with small animals. Experience with flow cytometry, western blot techniques, and working in a team environment a plus.
An understanding of lipid biology, protein chemistry, biochemistry, pharmacology, and signal transduction is preferred. Familiarity with in vivo or ex vivo microscopy a plus.
Please contact Dr. Holinstat at firstname.lastname@example.org with further questions.
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