Life Science Technician I (1-Year Fixed Term)-76224
About the Research Lab
We are investigating new image-guided minimally invasive therapies. The primary technologies we are investigating are focused ultrasound and cryoablation. Focused ultrasound uses a ultrasound beam focused to a point deep within the body. The tissue at the focal point may heat to the point of coagulation, which is intended for cancer therapy. Since the beam outside the target is spread out over a large area, there is no damage to the intervening tissue.
The current major focused ultrasound application areas we are working on are in the liver, prostate, and brain. Much of our work is done with the InSightec ExAblate focused ultrasound systems. The liver is particularly challenging because of the respiratory motion. We are developing MR thermometry methods that work during free breathing. In addition, we are investigating FUS in a tumor model of HCC. For the prostate, we are working with Chris Diederich at UCSF to develop transurethreal applicators for ultrasound ablation of the prostate. For the brain, we are investigating the blood brain barrier opening applications. In these areas, we are developing magnetic resonance guidance methods including MR thermometry, MR acoustic radiation force imaging, and methods for assessing the the underlying state of the tissue after these interventions with diffusion-weighted, magnetization transfer, and contrast enhanced MRI.
MR imaging of the prostate during cryoablation is particularly challenging because there is no MR signal from frozen tissue on conventional MR imaging sequences. In our research program, we are developing methods to image frozen tissue, relate MR-parameters of frozen tissue to temperature, and develop temperature maps of frozen tissue.
Other major projects include reduction of metal artifacts, dynamic MSK imaging, MR-guided vascular interventions, and development of a fully integrated X-ray and MRI System. Links to our projects and collaborations can be found from the list on the left, as well as other information about the lab.
About the Position
The Department of Radiology is seeking a 1-year fixed term Life Science Technician I who under the direction of the department will be responsible for performing experiments on lab animals to determine the results of applying ultrasound to the brain, measurements on EMG and other recording devices at the Radiological Sciences Laboratory at Stanford School of Medicine.
Conduct experiments on lab animals using culture techniques while applying ultrasound to the brain
Very simple animal dissection such as removing a readily accessible organ, preparation before and assistance during surgery, administration of medication and post-surgery care
Assist lab members, including students, lab technicians and postdoctoral fellows, with their research projects including providing technical expertise
Maintain lab and equipment
Knowledge of signal processing and computer skills
Good organizational and computer skills
College science background is required
At least one years employment experience in laboratory or equivalent training (e.g., one year of college science)
Ability to follow detailed instructions and keep accurate records.
College degree and understanding of the basics of ultrasound wave propagation
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