Job Posting: Under general guidance, the Research Associate III works closely with Pl, providing technical and/or administrative support in multi-project oriented labs. May be requested by Pl to take on specific supervisory activities and provide technical expertise and administrative leadership. May develop hypothesis and assist in planning steps for the investigative process. Will review and remain current on literature as it relates to translational research study. Coordinates all lab activities including but not limited to the safe handling and processing of biospecimens, provision of technical support, compliance with laboratory safety regulations, budgetary/financial compliance, ordering supplies, day-to-day supervision of graduate students and fellows, preparation of grant proposals and creating independent presentations. Not responsible for generating grant funds. Essential Job Duties and Responsibilities
Provide technical support in the laboratory, including: Safe handling and processing of clinical samples (such as human blood, saliva, and formalin fixed paraffin embedded (FFPE) tissue blocks); Sterile cell culture; Conduct genetic, epigenetic, and other molecular biology protocols accurately and reproducibly to generate original data from clinical specimens; Microdissection of FFPE tissue samples; Sectioning FFPE tumor blocks; generation of tissue microarrays; DNA and RNA extractions from fresh, frozen, and FFPE tissues; cDNA synthesis and reverse transcriptase PCR; PCR and real-time PCR; Generation of libraries for next generation sequencing, exome sequencing, whole genome sequencing and whole genome bisulfite sequencing; Cloning and culture of bacterial colonies containing recombinant DNA; Gel electrophoresis; Western blotting; Pyrosequencing; Sodium bisulfite conversion of genomic DNA for methylation analyses; ChIP. On-site training will be provided for essential techniques.
Provides miscellaneous research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.).
Organizes research projects in conjunction with the Principal Investigator and sponsor and/or funding source.
Analyzes data and prepares scientific findings for publication as author or co-author
Attend, contribute to, and present at laboratory group meetings
May provide system administrative and maintenance for the local workstation network.
Leads and trains incoming Graduates Students, Research Fellows, lower level Research Associates, and other related support staff and may be requested by Pl to take on specific day-to-day supervisory activities.
Orients new Research Fellows and/or Research Scientists to day-to-day lab operations and procedures
Manage the day to day running of the laboratory
Monitors and ensures compliance with safety standards and procedures, including maintenance of chemicals inventory
Assist with the establishment and maintenance of IRB proposals and protocols relating to projects in the laboratory
Establish and maintain Safety protocols and Standard Operating Procedures relating to projects in the laboratory
Undertake research projects that form part of the research program under the direction of the Principal Investigator
To manage equipment maintenance and purchasing in the laboratory
Maintenance of database and accompanying biorepository
Qualification Requirements/Preferences: Education Certifications/Licensure Experience Physical Abilities Educational Requirements: Bachelor of Sciences degree in biological sciences or related field. Experience: Minimum of three years of laboratory experience in area of research specialization. Has technical skills and expertise in an area of study including, but not limited to, Molecular/Cellular Biology, Neuroscience, engineering, or mass spectometry. Experience in cutting-edge histology/imaging techniques including quantitative bright-field and fluorescence microscopy, confocal microscopy, and electron microscopy is required. Strong computer skills (MS Word, MS Excel, MS Access, PowerPoint). Strong analytical and problem-solving skills; excellent organization skills and very detail-oriented; learns new tasks quickly; self-motivated; works well independently with minimal supervision; works well with others, and able to multitask. Strong interpersonal skills for interaction with peers, patients, physicians, and other customers of the medical center. Thorough technical and theoretical understanding of PI's research objectives. Mastery of complex or unusual technical procedures and protocols. Ability to research, develop and implement new laboratory procedures and protocols. Knowledge of human resource and administration policies and procedures. Knowledge of budgetary requirements and policies. Physical Demands: (e.g., lifting, standing, walking) Physical abilities necessary to perform job, including sitting or standing for extended periods, repeated pipetting by hand, and light-weight lifting.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scien...tists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.