UCLA’s Department of Microbiology, Immunology and Molecular Genetics is seeking to fill an Assistant Project Scientist position. The Assistant Project Scientist candidate will perform independent research on investigating the mechanisms of immune interactions with epithelial cancer pathogenesis.
The Assistant Project Scientist will also be responsible for performing research on isolating TCRs for directing an immune attack on cancer and be responsible for designing, planning and managing experiments for these projects in collaboration with other members of the group. The Assistant Project Scientist position is a 12 month non-Senate position.
Interested candidates should apply on-line on this site:
Perform research on isolating TCRs for directing an immune attack on cancer
Responsible for designing, planning and managing experiments for these projects in collaboration with other members of the group.
Conduct research to amplify efforts on identification and isolation of T cells from cancer patient’s tumor infiltrating lymphocytes, blood, as well as other sources for directing an immune attack on cancer.
Conduct studies to identify and characterize the interactions of T cells with other immune cell components with regard to T cell activation/inhibition.
Conduct studies to profile tumor-reactive T cells using surface markers and to identify the most effective ones for identifying and isolating tumor-reactive T cells.
Conduct studies to characterize T cells, including tumor specificity, MHC restriction, T cell activity and efficacy on tumor attack.
Conduct in Vitro studies in various co-culture settings to evaluate and quantify the activities of cloned T cells, including cytokine secretion, tumor killing and immune cell profiling.
Able to design experiments with a clear target to specific questions; able to interpret data and prepare data for publication; able to initiate new research project and plans.
Able to develop new assays and to improve the existing technologies/methods in adaptation of research’s new needs.
Skilled with routine lab techniques, such as tissue culture, cell line establishment/maintenance, T cell activation/expansion for in vitro and in vivo studies, PBMC isolation, tissue/blood processing, virus infection, FACS analysis, ELISA, intracellular staining, IncuCyte, etc.
Understanding the basic concepts of immunology and knowledgeable in the fields of cancer immunotherapy and immune cell engineering are a plus.
Able to conduct positive interactions and collaborations with peer researchers both internally and externally, and work effectively in a highly interactive environment.
Understand the dynamics of research, be able to quickly grasp the new directions of research development and apply new knowledge to studies.
Oversee undergraduates, graduate students and new postdoctoral trainees in the lab.
Ability to work on multiple projects efficiently and effectively.
Ability to work independently on scientific projects.
Required to communicate well with other scientists worldwide.
Candidate should have minimum 5 years research experience in biochemistry, molecular biology, cell biology and genomics in an academic setting or equivalent, PhD preferred
Candidate should have extensive experience in recombinant DNA techniques, PCR, cell culturing techniques, quantitative proteomics, animal research and bioinformatics.
The candidate will report directly to the Principal Investigator and will successfully carry out experiments and analyze the data generated with minimal to no supervision.
The candidate will be required to complete all appropriate safety training as mandated by the campus’s Environmental Health & Safety Office
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: UC Nondiscrimination and Affirmative Action Policy.
University policy is intended to be consistent with the provisions of applicable State and Federal laws.
The Department is Particularly interested in candidates who have experience working with students from a diverse background and a demonstrated commitment to improving access to higher education for disadvantaged students or The (School) at UCLA is committed to building a more diverse faculty, staff and student body as it responds to the changing population and education needs of California and the nation.
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