Cornell University's College of Engineering, the preeminent engineering school in the Ivy League, has a rich history of experimentation, innovation, and leadership. Consisting of almost 3,000 undergraduate students, 1,700 graduate students, and over 200 faculty members, Cornell Engineering is recognized as a global leader in the discovery of new knowledge and the creation of transforming inventions. Cornell Engineering students and faculty members possess an independent spirit that allows for the development of innovative interdisciplinary research, the creation of exciting new programs, and the education of students who will better the future.
The primary mission of Cornell University's Biomedical Engineering department is to educate students to understand the human body as an integrated system through quantitative engineering analysis and to use that understanding to design better therapeutic strategies, devices, and diagnostics. A mission of nearly equal importance is to serve society by conducting research that develops quantitative linkages across scales in the human body and uses that development to build new tools to improve human health.
The De Vlaminck lab will be working with collaborators from across the globe to perform a cross-cutting evaluation of the utility of metagenomic analyses of cell-free DNA in three different settings: (a) Environmental Enteric Dysfunction, (b) Tuberculosis, and (c) Soil-Transmitted Helminth infection.
Microbial cell-free DNA is present in the blood circulation and is the product of microbial degradation across the body, or originates from microorganisms that infect the blood or translocate to the blood. We will investigate the utility of metagenomic analyses of cell-free DNA as a (1) non-invasive tool to monitor the integrity of the gut-vascular barrier and the extent of bacterial translocation in Environmental Enteric Dysfunction, (2) as an early diagnostic and potential treatment monitoring tool in Tuberculosis, and (3) a screening tool for tissue and gut helminths that can be used for epidemiological mapping of pathogen presence within a population.
work with an interdisciplinary team of researchers to perform next generation sequencing analyses of the molecular heterogeneity in blood plasma samples.
perform and oversee sample preparations, conduct, design and maintain process quality control
assist in new technology development
manage sample banking and tracking
responsible for communicating with collaborators in different continents, and aiding in the logistics of this multi-team collaborative project
assist with data analyses and reporting to the funding organization
assist with additional laboratory projects that use similar technologies, as needed
This is a one-year term position; possibility of renewal based on available funding & performance.
Minimally an Associates Degree with 2 years of experience or a Bachelors degree in a relevant field ( multiple years of experience in working in biological research laboratories is preferred but not required)
Exceptional communication and organizational skills, manual dexterity, timely data generation, and excellent multitasking abilities are required.
Ability and desire to acquire new technical skills in the wet lab is required.
Basic skills in molecular biology sample preparation for next generation sequencing analyses are required.
Ability to develop positive working relationships with colleagues and collaborators is critical.
Computer skills, including use of MS Word, Excel, PowerPoint are required.
Must be willing to work in a team atmosphere
Visa sponsorship is not available for this position.
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