Posting Summary: The Miller Laboratory at the University of Virginia seeks a motivated and energetic postdoctoral research associate with a background in genetics, molecular biology or similar field to investigate the genetic basis of coronary artery disease. This project will focus on investigating the causal mechanisms of novel loci associated with CAD and will involve the generation of genomic datasets in normal and diseased environments. The primary goals of this project are: 1) to elucidate the role of genetic variation on transcription, TF occupancy and chromatin structure, 2) to perform targeted and multiplexed perturbation assays in vitro using CRISPR/Cas9 at candidate loci, 3) to validate candidate drugs or biomarkers in phenotypic screens for cardiovascular diseases.
The candidate will have access to state-of-the art facilities and will be exposed to a stimulating environment in the Center for Public Health Genomics (CPHG), led by Drs. Stephen Rich and Charles Farber. This work will involve close collaborations with members of the CPHG and the newly formed Data Science Institute. The candidate will also benefit from strong collaborations with members of the Robert M. Berne Cardiovascular Research Center and in the Departments of Biomedical Engineering and Biochemistry and Molecular Genetics.
Candidates must have a PhD or MD/PhD in quantitative life sciences field in hand by appointment start date. Expertise in human genetics, molecular biology, or similar field is expected. The successful candidate must be organized and independent, and have excellent written and oral communication skills. Knowledge in bioinformatics, genomics, and statistics are preferred, as is knowledge of genome editing and high-throughput screens.
To apply, visit https://jobs.virginia.edu and search on Posting Number 0621336. Complete a Candidate Profile on-line; attach a current CV, statement of research interests, and contact information for three references. The position will remain open until filled.
For additional information about the position, please contact Dr. Clint L. Miller (email@example.com).
The University of Virginia is an equal opportunity/affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.
Founded by Thomas Jefferson, the University of Virginia opened in 1825 as the nation's first public university. A longstanding dedication to preeminence in both scholarship and teaching; top ranking in global satisfaction, collegiality and work/family issues on the COACHE survey of early career faculty; a commitment to excellence that is integrally connected with diversity and a broad array of ben...efits make the University of Virginia a prime choice for both faculty and staff. The University of Virginia is located in the small cosmopolitan city of Charlottesville near the Blue Ridge Mountains, 70 miles from Richmond and 110 miles from Washington, D.C. The University of Virginia remains the No. 2 best public university in the 2013 edition of the U.S. News and World Report rankings. In the 14 years since U.S. News began ranking public universities as a separate category, U.Va. has ranked either No. 1 or No. 2. U.Va. continues to rank in the Top 25 among the best of all national universities, public and private.